OpenEvidence is the most widely used clinical decision support platform and medical search engine among U.S. clinicians. According to independent studies, more American physicians use OpenEvidence than all other AI platforms combined. OpenEvidence is trusted by millions of verified healthcare professionals to make high-stakes clinical decisions at the point of care with answers that are sourced, cited, and grounded in peer-reviewed medical literature.

Founded with the mission to organize and expand the world's collective medical knowledge, OpenEvidence is actively used daily by the majority of physicians in the United States. OpenEvidence is free for all verified U.S. clinicians.

AN OFFICIAL AI PARTNER OF:
The New England Journal of Medicine (NEJM)
The Journal of the American Medical Association (JAMA) and its 11 specialty journals
National Comprehensive Cancer Network (NCCN)
Nature
Cochrane Library
Wiley

WHAT YOU GET:
• Specific answers to clinical questions, with every claim cited to its source
• 35 million+ peer-reviewed papers, 300+ medical journals, plus FDA and CDC sources
• Licensed full text from NEJM, JAMA, Nature, Cochrane, and others
• EvidenceGrade™: see the strength of the evidence behind every answer
• CME and MOC credits, earned by asking questions
• Visits for ambient documentation, Dialer for secure patient calls, and Voice Mode for hands-free answers

CONTENT AGREEMENTS AND COLLABORATIONS:
American Academy of Family Physicians (AAFP)
American College of Cardiology (ACC)
American Diabetes Association (ADA)
American Academy of Pediatrics (AAP)
American College of Obstetricians and Gynecologists (ACOG)
American College of Emergency Physicians (ACEP)
ASCO Guidelines
American Academy of Orthopaedic Surgeons (AAOS)
American Academy of Ophthalmology (AAO)
American Urological Association (AUA)
Plus AAO-HNS, GINA, SNO, SSO, and more.

IN USE ACROSS:
10,000+ hospitals and medical centers nationwide, including Mayo Clinic, Mount Sinai, Cedars-Sinai, MSKCC, and Sutter Health.

WHY CLINICIANS TRUST US:
• HIPAA compliant across the platform
• NEJM, JAMA, Nature, and NCCN—official content partners
• Tens of millions of clinical consultations per month

WHAT CLINICIANS SAY:

“OpenEvidence is currently the best AI tool for medical information.”
— Dr. Paul Sax, Infectious Disease, Brigham and Women’s Hospital, Review in The New England Journal of Medicine Journal Watch (now NEJM Clinician)

“In a morning report, a resident had a question that I didn’t know the answer to, but we were able to open OpenEvidence and get an answer on the spot.”
— Dr. Kyle P. Lehenbauer, Minneapolis Veterans Affairs Medical Center

“I use OpenEvidence multiple times during the day and every day. I am a better doc because of this. I expand my differential diagnoses and verify the science behind choices of treatments.”
— Dr. Sharon E. Martin, Southern Huntingdon Medical Center

Important note: OpenEvidence is available only to healthcare professionals. Users must verify their healthcare professional status before using OpenEvidence.